Evaluation of Bone Repair in the Mandible of Rabbits Using Biphasic Calcium Phosphate Micro-Macroporous Hydroxyapatite Bioceramics and Beta-Tricalcium Phosphate

Objective: To perform a clinical and histological evaluation, characterizing and proving the feasibility of the use of beta tricalcium phosphate (HA/ßTCP) bioceramics as a bone defect repair material, comparing it with autogenous bone and blood clot in terms of osteoinductive, conductive, and genic capacities. Material and Methods: The experiment was based on 3 critical defects in the mandible of 11 New Zealand rabbits. The defects were filled with HA/ßTCP bioceramics and autogenous bone, respectively, collected and ground during the development of defects and blood clots. The animals were euthanized after the 90-day experiment and samples were collected for histomorphological examination. To evaluate differences between the groups, a one-way analysis of variance (ANOVA) was performed with Tukey's post hoc test. An α value lower than 0.05 was considered statistically significant. Results: Microscopy revealed the presence of osteoblasts, osteoclasts, and osteocytes associated or not associated with the presence of mature or immature bone. All the studied materials presented bone neoformation in all cases, with the presence of mature and immature bone. Regarding the presence of HA/ßTCP bioceramic residual material, the same was found in 7 of 11 slides. Conclusion: HA/ßTCP bioceramics were shown to be a biocompatible bone substitute, with osteoinductive and osteoconductive characteristics, accelerating the process of new bone formation when compared with autogenous and blood clotted bone, thereby showing promise for bone defect repair with safety and efficacy.

Prevalência de lesões orais na I Campanha de Prevenção do Câncer Bucal no município de Osasco / Prevalence of oral injury in First Campaign of Prevence of Buccal Cancer in Osasco

Este estudo é baseado em dados obtidos na Campanha de Prevenção do Câncer Bucal realizada no município de Osasco em 1997. Nesta campanha foram examinadas 5.326 pessoas das quais 211 compareceram a fase de tratamento clínico e foram submetidas a procedimentos de biópsia. Esta Campanha teve como objetivo diagnosticar, tratar e analisar através de levantamentos estatísticos a prevalência de lesões bucais no município, demonstrando a importância desta campanha para a comunidade

Rânula: aspectos clínicos. Qual a melhor opção terapêutica? / Ranula: clinical aspects. Which the best therapeutic choice?

Rânula - fenômeno de retenção de muco localizado especificamente em assoalho de boca, associado aos ductos das glândulas salivares submandibulares e sublinguais. Este, considerado como um cisto de retenção, tendo na sua etiologia fatores ou causas oriundas de um trauma regional ou ainda, obliteração dos ductos salivares secretores das glândulas salivares submandibulares e sublinguais por processos inflamatórios e ou infecciosos e também a formação de cálculos salivares volumosos do interior dos canais. Tendo na sua terapêutica de eleição, a cirúrgica, com a remoção total ou parcial da lesão, pode ser realizada através da micromarsupialização, da marsupialização e da enucleação e em alguns casos a remoção integral da glândula salivar lesada